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curcumin in korean

The importance of this medicinal plant as a spice and in folk medicine, not only in Asian countries but also in the western world, prompted the growing research with turmeric extracts and their main constituents over the past 30 years (see Fig. We all are aware that Turmeric is very good for good health Curcumin is made up of pure turmeric extract and I had full faith on it. Curcumin (110 mg/kg daily for 28 days) delayed and improved joint abnormality and injury in rodents with collagen-induced arthritis and it was suggested that these effects may be mediated by suppression of B cell-activating factor (Laev and Salakhutdinov, 2015). ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780080453828000228, URL: https://www.sciencedirect.com/science/article/pii/B9780123849472001896, URL: https://www.sciencedirect.com/science/article/pii/B9780128053775000126, URL: https://www.sciencedirect.com/science/article/pii/B9780123786388000087, URL: https://www.sciencedirect.com/science/article/pii/B9780323527279000212, URL: https://www.sciencedirect.com/science/article/pii/B9780128054178000287, URL: https://www.sciencedirect.com/science/article/pii/B9780128125045000118, URL: https://www.sciencedirect.com/science/article/pii/B9780123971548000440, URL: https://www.sciencedirect.com/science/article/pii/B9780128130087000266, URL: https://www.sciencedirect.com/science/article/pii/B9780128018163000352, Natural Products Structural Diversity-I Secondary Metabolites: Organization and Biosynthesis, Colors: Properties and Determination of Natural Pigments, Pancreatic Cancer, Pancreatitis, and Oxidative Stress, An Objective Appraisal of the Free Radical Theory of Aging, Michael Lustgarten, ... Holly Van Remmen, in, Handbook of the Biology of Aging (Seventh Edition), Nanostructures for Curcumin Delivery: Possibilities and Challenges, Parasuraman A. Subramani, ... Venkata Ramireddy Narala, in, Nano- and Microscale Drug Delivery Systems, Phytochemicals as Anti-inflammatory Nutraceuticals and Phytopharmaceuticals, Immunity and Inflammation in Health and Disease, Hatcher et al., 2008; Schaffer et al., 2011; Shehzad et al., 2011; Howes and Simmonds, 2014; Lu and Yen, 2015; Ghosh et al., 2015; Pulido-Moran et al., 2016, Panahi et al., 2014; Rahimnia et al., 2015, Polyphenols in Obesity and Metabolic Syndrome, Belén Pastor-Villaescusa, ... Oscar D. Rangel-Huerta, in, Phytochemicals Are Effective in the Prevention of Ethanol-Induced Hepatotoxicity, Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease, Aggarwal and Shishodia, 2006; Hatcher et al., 2008, Bao et al., 2010; Naik et al., 2004; Rukkumani et al., 2004a, Hepatoprotective Effects of Curcumin in Alcohol-Induced Hepatotoxicity: A Memoir on the Preclinical Studies, Manjeshwar Shrinath Baliga, ... Princy Louis Palatty, in, Polyphenols: Prevention and Treatment of Human Disease (Second Edition), Mechanisms of Action of Curcumin on Aging, Ana C. Carvalho, ... Cristovao F. Lima, in, Journal of Traditional and Complementary Medicine. Curcumin … You should drink Korean Nano Tech Curcumin 365 after breakfast. (yellow pigment) curcumina nf nombre femenino: Sustantivo de género exclusivamente femenino, que lleva los artículos la o una en singular, y las o unas en plural. Curcumin is the main curcuminoid found in the rhizome of the perennial plant C. longa Linn, a member of the ginger family (Zingiberaceae). Curcumin is the principal polyphenolic compound present in turmeric with broad applications in tissue engineering and regenerative medicine. Curcuma longa is indigenous to South and Southeast Asia but is nowadays widely cultivated in tropical areas of Asia and Central America. In two RCTs, participants with knee osteoarthritis (n=19 for both studies) administered 1500 mg curcuminoids daily showed improvements in clinical symptoms and in one study, significantly lower serum levels of IL-4, IL-6 and high-sensitivity C-reactive protein were also observed; however, other inflammatory parameters were not significantly affected, thus the improvements in clinical symptoms were not attributed to the anti-inflammatory effects of the curcuminoids (Panahi et al., 2014; Rahimnia et al., 2015). Estimation of curcumin intake in Korea based on the Korea National Health and Nutrition Examination Survey (2008-2012) Nutr Res Pract. With regard to hepatoprotection, studies have shown that both turmeric and curcumin are effective against a myriad of hepatotoxins and have beneficial effects similar to silymarin [5,15,16]. Type: noun; Copy to clipboard; Details / edit; agrovoc. [94] found that during hypoxia in 3T3-L1 adipose cells, the administration of curcumin reduced the production of inflammatory mediators (e.g., leptin, resistin, TNFα, NF-κB, c-Jun N-terminal kinase, and serine phosphorylation of IRS-1 receptors), restored the antiinflammatory adipokines (e.g., adiponectin) to the normal level, and also improved insulin sensitivity. Curcumin is the amazing active compound that is found within the turmeric rhizome (curcuma longaCurcuma longa). How to use NanoTech Curcumin 365.You can mix 1 tube of Korean Nano Essence 365 Curcumin with filtered water or dissolve with fruit juice, milk, tea about 200-300ml, ... or put in the same food every day.Note that when mixing Korean 365 Korean Curcumin Essence in food, it is very easy to use and achieve higher efficiency. Similarly, Na et al. Curcumin has been identified as one of the main active compounds responsible for turmeric’s effects. Another study using 20 mg/day of curcumin for 15 days in human subjects with atherosclerosis significantly lowered the levels of plasma fibrinogen in both men and women [99]. Several strategies have been used to improve the bioavailability of curcumin by technological treatments [81]. Scheme 16. In addition, in the Indian subcontinent, turmeric mixed with slaked lime has been used topically as a household remedy for the treatment of wounds, inflammation, burns, and skin diseases [11,13]. Chitosan with low, middle and high molecular weight (3 kDa, 30 kDa and 190-310 kDa respectively) was applied for coating the prepared NE. Curcumin has been shown to reduce the expression of potent proinflammatory adipokines, such as IL-6, TNFα, MCP-1 [90,92], and plasminogen activator inhibitor type-1 (PAI-1), and to induce the expression of adiponectin and delay preadipocyte differentiation [90]. ADDRESS. Curcumin is a bright yellow chemical produced by Curcuma longa plants. It generically consists of two ferulic acid residues joined by a methylene bridge, and exhibit two main tautomeric forms (Fig. Figure 35.2. Curcuminoids (especially curcumin) are the active ingredients of the dietary Indian spice turmeric and are extracted from the rhizomes of Curcuma longa, a plant in the ginger family which has been used for medicinal purposes for years, mostly in Asian countries. The words Turmeric and Curcumin are often used interchangeably, but the difference between the two is important. Curcumin is a yellow-orange hydrophobic compound insoluble in water and ether but soluble in dimethylsulfoxide, acetone, ethanol, and oils. Interestingly, the mechanism of the formation of curcuminoids is very different from the traditional head-to-tail model of polyketide assembly. Tetrahydrocurcumin (TC) is a curcuminoid metabolite and has been shown to act as an antioxidant (Osawa et al., 1995). Since absorption is limited through oral administration, highly bioavailable forms of curcumin such as Theracurmin have been developed for its clinical application [99]. In addition to these, inside a human body, curcumin rapidly gets metabolized into many different end products. Exemplos: la mesa, una tabla. Three spots were seen in all the samples at the similar Rf values. Curcumin is the primary curcuminoid in turmeric and the compound for which most studies have been done. The diketide-CoA is converted into β-keto acid (129) by hydrolysis, which finally condenses with another molecule of feruloyl-CoA (25) to produce curcumin (127). curcumin - Translation to Spanish, pronunciation, and forum discussions. Times, Sunday Times (2006) Curcumin speeds up blood flow, so reduces stickiness and effectively cools your body. A number of preclinical studies have demonstrated anticancer effects of curcumin and other curcuminoids in various types of tumors including pancreatic cancer. A less common analog of curcumin, cyclocurcumin, is also naturally found in C. longa although in low proportions. During the course of the reaction, the diketide CoA is converted into the corresponding β-keto acid by hydrolysis, which is then condensed with another molecule of aromatic CoA to produce curcuminoids. 20 Since 1815, when the first report of extraction and purification of curcumin was published, the curcumin extraction method has been continuously improving and … In traditional Chinese medicine, it is used to treat diseases associated with abdominal pain [2], and as a major constituent of Jiawei-Xiaoyao-san medicinal formula, C. longa has been used to manage dyspepsia, stress, and depression/mood-related ailments [12]. Acute and chronic inflammation is a major factor in the progression of obesity, type II diabetes, arthritis, pancreatitis, cardiovascular, neurodegenerative and metabolic diseases, as well as certain types of cancer. Shivashankara, ... M.S. Examples of how to use “curcumin” in a sentence from the Cambridge Dictionary Labs To start with, curcumin is obtained from the spice turmeric, a member of the ginger family while cumin belongs to the parsley family. Loading ability and efficiency of curcumin were 0.548 mg/mL and 95.10% respectively which indicated its water dispersibility was increased by 1400 fold. We use cookies to help provide and enhance our service and tailor content and ads. A major food source of curcumin in the Korean diet might be curry. Scientific studies have shown that curcumin possess antitumor, antioxidant, antiarthritic, antiamyloid, anti-ischemic, and anti-inflammatory properties (Aggarwal and Shishodia, 2006; Hatcher et al., 2008). In patients with metabolic syndrome, those receiving curcuminoids (n=59) in a RCT at a dose of 1 g daily (with 10 mg piperine to improve bioavailability), had reduced serum CRP levels (Panahi et al., 2015), indicating curcuminoids may have clinical benefits on inflammatory status in metabolic disorders. The public interest in the wide range of effects of curcumin paved the way to its commercial use worldwide in several products (Fig. Curcumin and cumin may sound similar, however, they are starkly different from each other in a number of ways. However, evidence agrees with the hypothesis that curcumin directly interacts with WAT to suppress chronic inflammation. Curcuminoids with ω-3 fatty acids and botanical antioxidants including polyphenols, tocopherols, and rosemary extract induced high caspase-3 activity in pancreatic ductal adenocarcinoma cells and potentiate natural killer cells’ cytocidal function [100]. Free Shipping IN the USA on orders over $50. Multiple signaling pathways are involved in curcumin’s regulatory effects, including NF-κB, Nrf2, STAT3, AKT, MMPs, VEGF, Notch1, Cox-2, ATM/Chk1, WT1, and so on [102,103]. Thus, the amount of curcumin that can be obtained from the Korean diet in a day is 2.7-14.8 mg, corresponding to nearly one fourth of the daily curcumin intake in South Asia, although curcumin is rarely consumed in Korea. Curcumin is reported to possess a myriad of cellular and physiological effects on various cells and several mechanisms, such as increasing the cell's antioxidant enzymes; suppressing inflammatory players like COX-2, LOX, TNF-α, and IFN-γ; and modulating the signal transduction (MAPK) and transcription factors (NF-κB and Nrf2) [19,23,26]. A dose of Korean Curcumin Gold Korea will help your special dishes, grilled dishes, become more attractive. chemical compound. - Cucu E100 … Curcumin consumption has not yet been estimated in Korea. In the past, they were neglected and were often considered to be contaminants of curcumin. Using curcumin, the spice's yellow chemical, also caused fewer sideeffects. Belén Pastor-Villaescusa, ... Oscar D. Rangel-Huerta, in Obesity, 2018. 35.2): the keto-enol form (also known as enol form) and the diketo form (also known as keto form). An important mechanism of curcumin reported in in vitro studies is the activation of Nrf-2, a transcription factor and master regulator of antioxidant responses, affecting the expression of hundreds of cytoprotective genes controlling antioxidant enzymes and immune responses [90]. Lyophilized powder of Cur‐TPGS NSs was dissolved about 91.08% whereas the pristine curcumin … Estimation of curcumin intake in Korea based on the Korea National Health and Nutrition Examination Survey (2008-2012) By Youngjoo Kwon. All these phenomena might offset the symptoms associated with obesity and metabolic diseases [92,93]. With regard to the protective effect of curcumin against alcohol-induced hepatoxicity, studies have shown that curcumin mitigated the oxidative stress and prevented liver cell damage in experimental animals (Bao et al., 2010; Naik et al., 2004; Rukkumani et al., 2004a). Ana C. Carvalho, ... Cristovao F. Lima, in Molecular Basis of Nutrition and Aging, 2016. Among them, curcumin is considered the most important biomedical molecule. Turmeric is frequently used in Asian cooking, particularly in India, Pakistan, and Thailand, to improve the palatability and presentation of food preparations. Body weight of the mice on the TC and the control diets was not significantly different from 19 months onward (Kitani et al., 2007). Composition for the treatment of skin flaps, comprising curcumin as an active ingredient. Morning is always the best time for the medicine to absorb. In the old Hindu texts of traditional medicine of Ayurveda (meaning knowledge of long life), turmeric is recommended for its aromatic, stimulant, and carminative properties [11]. About Sabinsa Sabinsa Corporation is a manufacturer, supplier and marketer of herbal extracts, cosmeceuticals, minerals, dietary supplements and specialty fine chemicals for the nutritional, cosmetic, pharmaceutical and food industries. - Korean Curcumin Nano 365 Curcumin Korea contains thrombomodulin so it helps support the treatment of bacterial or viral infections, establishing an effective immune system. Figure 28.9. Curcumin has been shown to reduce sugar and lipids levels in many ways. Curcuminoids such as curcumin (Fig. CONCLUSIONS: Thus, the amount of curcumin that can be obtained from the Korean diet … Baliga, in Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease, 2013. 35.1). Manjeshwar Shrinath Baliga, ... Princy Louis Palatty, in Polyphenols: Prevention and Treatment of Human Disease (Second Edition), 2018. Curry (37.24–617.98 μg g − 1), especially curry powder, mustard, candy, pickle, and snack food types, exhibits the highest curcuminoid content among various food items in Korean markets. A curcuminoid supplementation of 1 g/day combined with piperine (95%) for 30 days leads to a significant reduction in serum TG concentrations as well but do not on other lipids, neither on BMI or body fat in obese patients [97]. From Curcuma longa to turmeric to curcumin: its traditional and commercial uses. Curcumin in Food, Pharma and Cosmetics ... Later, he joined Sejong University in South Korea as a Postdoctoral Scientist. Bradford PG. Water solubility of curcumin was significantly improved from 0.6 μg/mL in pure water to 260 μg/mL in the mixture of curcumin and TPGS (1:10) with UH treatment. The dysregulation of cell signaling pathways by the gradual alteration of regulatory proteins is the root cause of cancers. October 2016. Curcumin Versus Turmeric Curcumin is a naturally-occurring chemical compound found in the spice turmeric. In fact, curcumin is an approved natural food coloring (E100) additive that is used at low concentrations in butter, canned fish, cheese, mustard, pastries, and other foods [9]. The mean particle size of Cur‐TPGS NSs was decreased significantly after UH and maintained between 208 and 246 nm. Moreover, dietary supplementation with curcuminoids is reported to increase the hepatic acyl-CoA and prevent the lipid accumulation induced by an HFD in liver and adipose tissue of rats, as well as improving IR [33]; In HFD-induced obesity and insulin-resistant mice, its oral administration proved to be effective in reducing glucose intolerance [96]. Another study showed curcumin can reduce oxidative stress in the brain and exert a protective effect against certain toxins – two problems frequently found in children with autism. Molecular studies have also shown that administration of curcumin to rats with alcohol-induced liver disease prevented the activation of NF-kB and suppressed the expression of cytokines, chemokines, COX-2, and iNOS in Kupffer cells of liver (Nanji et al., 2003). In Europe, curcumin is known as E100 food additive (turmeric or curcumin), which is widely applied to several food items (e.g., smoked fish, savory snacks, sauce, mustard, and seasoning) and to fabrics. Korean Nano Tech Curcumin 365 is composed of the following main ingredients:- Nano curcumin: this is a preparation from yellow turmeric which has an extremely good antioxidant effect, high anti-inflammatory, and antiviral properties. Korean Curcuma longa L. Induces Lipolysis and Regulates Leptin in Adipocyte Cells and Rats. Many of the biological activities attributed to turmeric were confirmed by experimental scientific studies, such as its antimicrobial, antioxidant, and anti-inflammatory properties [2,8,14,15]. It has long been used as food, coloring agent, and traditional medicine. The use of curcumin is mainly limited because of its poor pharmacokinetic and pharmacodynamic profile: poor absorption, short half-life, and rapid metabolism in the gastrointestinal tract [84]. b Curcumin is a component of turmeric.c The chemical structure of curcumin demonstrates a bis a, b-unsaturated diketone structure that displays keto enol tautomerism, with a predominant keto form in acidic and neutral solutions and a stable enol form in alkaline media. - Korean Nanotechnology Essence 365 Curcumin helps Detox the body, effectively supporting weight loss and body detox. In the following sections the hepatoprotective effects of curcumin and the mechanism/s responsible for the beneficial effects against ALD are described in detail. Curcumin has also been considered as a nutraceutical to maintain joint health, as indicated from a range of studies (Mobasheri et al., 2012). It is able to do so by decreasing glycaemia and dyslipidaemia in high fat-fed rats, decreasing blood glucose and antioxidant defences. Na et al. It is the principal curcuminoid of turmeric, which is a member of the ginger family (Zingiberaceae). Studies have shown that curcumin is a free radical scavenger and hydrogen donor and, depending on the dose and schedule, can exhibit both pro- and antioxidant activity [23]. Hiroyuki Morita, ... Hiroshi Noguchi, in Comprehensive Natural Products II, 2010, Curcuminoids, the major components of turmeric, are widely used as a traditional medicine and as food additive for their unique aromatic and coloring properties. TLC studies were carried out for the pure drug and its selected solid dispersions using chloroform: methanol (9.25:0.75) mobile phase on a silica gel G stationary phase. Turmeric also has been included for centuries in preparations of traditional Indian and Chinese medicine to treat various conditions such as allergy, anorexia, asthma, biliary disorders, bronchial hyperactivity, cough, diabetic wounds, liver disorders, rheumatism, rhinitis, sinusitis, sprains, and swelling [10]. The turmeric plant C. longa naturally possesses two major congeners of curcumin namely demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC). Recently, besides these effects, C. longa extract has been shown to improve insulin-mediated lipid accumulation (lipotoxicity) in adipocytes exposed to oxidative stress and increase the secretion of insulin-sensitising adipokines in 3T3-L1 adipose cells [92]. Curcumin also reduced repetitive, obsessive behaviors in the rats. Among them, a significant increase in its bioaccessibility was obtained by an excipient food emulsions technique [87] and nanotizing curcumin or combining it with piperine [88]. In vitro studies with the liver slice culture have shown that curcumin decreased lipid peroxidation, reduced the release of LDH, and attenuated the antioxidant enzymes SOD, CAT, and GSH-Px (Naik et al., 2004). A. Giuliani, ... A. Cichelli, in Encyclopedia of Food and Health, 2016. Apart from curcuminoids, C. longa is also the store house of bioactive compounds, like ar-turmerone, turmerone, and curlone. Phase I/II clinical trials showed that survival time/rate and quality of life have been improved without cumulative toxicity after oral administration of curcumin alone or in combination with Gem in patients with pancreatic cancer. During the reaction, 4-coumaroyl-CoA (3) also serves as a second extender to the diketide-CoA intermediate (130), leading to the formation of bisdemethoxycurcumin (17). Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) corresponds to about 2–5% of turmeric and was first isolated in 1815 by Vogel and Pelletier, with its chemical structure determined by Milobedzka and colleagues in 1910 (Fig. Nutrition Research and Practice. Curcuminoids (especially curcumin) are the active ingredients of the dietary Indian spice turmeric and are extracted from the rhizomes of Curcuma longa, a plant in the ginger family which has been used for medicinal purposes for years, mostly in Asian countries. Recently it was shown that in water containing mixtures, the keto tautomeric form of curcumin increases and dominates with a high percentage of water [6]. Curcuminoids are the main yellow pigments found in turmeric (Curcuma longa), the traditional Indian spice. – Mrs.Meera Anand. Studies have shown that curcumin is useful in the management of exercise-induced inflammation and muscle soreness and helps in speeding recovery and performance in active people [29]. Translation for 'curcumin' in the free English-Polish dictionary and many other Polish translations. Indeed, curcumin is suggested to have potential therapeutic relevance against inflammatory bowel disease (Brumatti et al., 2014) and a Cochrane Database review in 2012 concluded that curcumin may be a safe and effective therapy for maintenance of remission in ulcerative colitis as adjunctive therapy with conventional anti-inflammatory drugs, although larger scale RCTs are needed to confirm these benefits (Garg et al., 2012). Curcumin (diferuloylmethane), an active constituent of turmeric, is a well‐described phytochemical, which has been used since ancient times for the treatment of various diseases. (A) BV2 cells were treated with various concentrations of curcumin (5, 10, and 20 μM) for 24 h.(B) BV2 cells were preincubated with curcumin (5, 10, and 20 μM) for 1 h, and then exposed to LTA (5 μg/ml) for 24 h. Cell viability was measured by MTT assay. Nano Curcumin also has the ability to fight degeneration, reduce cholesterol and disable cancer cells. Curcumin (127) has received a great deal of attention because of its anti-inflammatory, anticarcinogenic, and antitumor activities.96–98 It has been proposed that curcuminoid scaffold is synthesized by a three-step reaction from phenylpropanoids (Scheme 16).99 First, malonyl-CoA (1) condenses with feruloyl-CoA (25) to produce a diketide-CoA (128). [92] observed a reduction in the intracellular levels of ROS and modulation of the expression of genes encoding SOD and catalase antioxidant enzymes by C. longa extract. Curcumin definition: a yellow pigment , derived from the rhizome of Curcuma longa , and the main active... | Meaning, pronunciation, translations and examples A separate RCT with 36 dementia patients (2 g or 4 g curcuminoids daily for 48 weeks) also concluded a lack of efficacy (Venigalla et al., 2016). Effect of curcumin on BV-2 microglial cell viability. Unfortunately, the life-span-extending effect in TC-supplemented mice may be ascribed to TC-fed animals having a significantly lower body weight (suggesting they may be caloric restricted) during the first 6 months of TC feeding. Although turmeric is thought to possess therapeutic properties, the curcuminoids complex found in … Although curcumin has been associated with numerous mechanistic effects (including anti-inflammatory activity) that suggest it may improve cognitive functions in dementia patients, in a small RCT, a daily dose (1 g or 4 g) of curcumin did not protect against cognitive decline in 27 patients with Alzheimer’s disease (Howes and Perry, 2011). Each day you can drink 2 tubes to get the best effect. FIGURE 1. Little is known about its exact underlying molecular mechanisms in the treatment of obesity and metabolic diseases. The pleiotropic and multitargeting capability of curcumin combined with its apparently safe profile identified it as a potential therapeutic phytochemical against cancer, lung and liver diseases, aging, neurological diseases, metabolic diseases, and cardiovascular diseases [7,12]. Curcumin longa L. (turmeric) contains 2%–9% curcuminoids, including curcumin, demethoxycurcumin and bis-demethoxycurcumin, and cyclic curcumin. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. Curcuminoids are natural polyphenol compounds derived from turmeric, which is a member of the ginger family (Zingiberaceae). curcumin . Regarding the impact on health, experimental studies support the activity of curcumin in promoting weight loss and reducing the incidence of obesity-related diseases [89,90]. These features can possibly be attributed to the methoxy, hydroxyl, α-, β-unsaturated carbonyl moiety, and diketone groups present in curcumin [83]. Curcumin, the principal curcuminoid of the popular Indian spice turmeric is arguably one of the highly investigated phytochemical. In adipocytes, curcumin also decreased TNF-α, IL-1β, IL-6 and COX-2 gene expression (Siriwardhana et al., 2013). The source and chemistry of curcumin. For example, the promotion of wound healing by turmeric was confirmed for curcumin from preclinical to intervention studies in humans [2,16–18]. Absorption and bioavailability studies in in vivo condition are required to clarify the beneficial effect of these bioactive compounds in human health. In contrast, in mice that started to receive TC in their 19th month of life no significant difference in either mean or maximal life span was found. It was first discovered about two centuries ago when Vogel and Pelletier reported the isolation of a “yellow coloring-matter” from the rhizomes of Curcuma longa (turmeric) and named it curcumin.

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